NutrigeneticsApplying the Science of Personal Nutrition
Fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even most modern humans. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests plus the ethics involved.
The challenge is to find out what nutrient amounts and which foods work best for an individual when there are so many potential differences. Most chronic nutrition-related diseases are in part caused by a mismatch of food and individual needs.
Continue with evidence-based courses such as this one that challenge and stretch us with higher level information and thinking requirements. – Mary Anne D. 5/31/22
Thank you for this well written course. It has pertinent information regarding differences in genetics and response to nutrition interventions that makes sense in my practice. I appreciate this as a further resource, and when things clinically are not stacking up, that I can reflect on genetics, change the course of diet intervention. It also allows for sensitivity to patients based on differences in genetics. - Ann D., RDN 3/30/22
Great book. I would recommend to anyone that would like to optimize their health. - B. Burke 12/20/16
Level 2 & 3 CPE
Suggested Performance Indicators: 1.1.4, 1.1.6, 1.1.8, 1.2.1, 1.4.1, 1.4.2, 1.4.4, 2.1.3, 4.1.1, 4.1.2, 4.2.6, 4.2.7, 6.1.9, 6.2.2, 6.2.3, 6.3.7, 6.3.8, 8.1.1, 8.1.5, 8.2.2, 8.2.3, 8.3.1, 8.4.4, 10.2.4, 13.2.3, 10.2.11, 10.3.1, 10.5.3
CPE Type: 720 for Printed/Paper Tests, 740 for Web-based/Online Tests
Upon successful completion, the users will be able to:
1. Explain two possible uses of the Online Mendelian Inheritance in Man catalogue.
2. Describe one significance of each variant and its effect on a person’s diet: methylene tetrahydrofolate reductase (MTHFR), hemochromatosis-related gene, and F5 Leinden of coagulation factor V.
3. Discuss one way genetic sequencing can help predict nutritional triggers that produce undesirable outcomes.
4. Define and contrast genotype, phenotype, and polymorphisms.
5. Give an example using food of how an epigenetic change occurs.
6. Contrast the terms: haplotype, memetic transmission, and imprinting.
7. Define “nutritional relativism” and give an example.
8. Discuss “nutritope” and its significance to a person’s food intake.
9. Describe two reasons why aborigines exposed to the traditional Western diet develop diabetes.
10. Identify the most frequent genetic disease in Caucasians and Blacks.
11. Describe how artificial sweeteners interact with a person’s body.
12. Explain the connection between umami sensitivity and eating meat.
13. Discuss the two contributing factors that influence the ability to taste salt.
14. Identify the oil that would help a person avoid insulin resistance if they have two A alleles of the rs682447 ELOVL6 gene.
15. Identify the genotype likely to make the person a cholesterol hyperresponder.
16. Identify the sugar a person with hereditary fructose intolerance can consume safely.
17. Describe how being heterozygous for loss of vitamin D is associated with multiple sclerosis.
18. Discuss what food men with the responsive allele for prostaglandin-endoperoxide synthase (PTGS2) need to eat for their health.
19. Identify what percent of a person’s BMI is based upon genetics.
20. Identify the cancer medication that works by inhibiting dihydrofolate reductase (DHFR).
21. Explain the best way to protect the confidentiality of genetic testing results.
Why we chose this book
Nutrigenetics and personal nutrition are coming areas of practice in medicine and it is time for practitioners to learn the basics.
About the author
Dr. Martin Kohlmeier, MD, PhD, is a Professor of Nutrition; Director of the Human Research Core and the Nutrigenetics Laboratory at the UNC Nutrition Research Institute in Kannapolis, NC; Director of Nutrition in Medicine for online nutrition education of medical students and health professionals; visiting fellow of Wolfson College at Cambridge University, UK; founding Editor-in-Chief of BMJ Nutrition, Prevention and Health; and President of the International Society of Nutrigenetics/Nutrigenomics (ISNN). His professional interests include investigating genotype-specific nutrition responses of humans in health and disease, developing decision-support algorithms and tools for precision nutrition, and teaching health care professionals how to use nutrigenetics in practice. His previously authored textbooks in the field include Nutrigenetics (Academic Press, 2013) and Nutrient Metabolism (2nd Edition, Academic Press, 2015).